Human-centered design (HCD) is a problem-solving approach that centers people’s experiences, pain points, needs, and desires in the solution development process. HCD is increasingly being used in health systems and patient-centered innovations, including for the specific goal of designing equitable solutions with marginalized populations.  Yet, few HCD efforts explicitly engage users who do not speak the dominant language of the design team, which is often English. Language discordance between end users and the design team opposes the fundamental tenets of HCD and needs to be addressed in pursuit of equitable solutions designed for minoritized linguistic communities.