The timely, effective adoption and implementation of evidence-based practices, interventions,
tools, programs, and policies (hereafter referenced as evidence-based practices) is important to improve health care delivery and patient outcomes. Implementation science (IS), user-centered design (UCD), and human-centered design (HCD) are three research approaches that focus on translating research evidence into the real world. In their recent article titled “A glossary of user-centered design strategies for implementation experts,” Dopp et al. [1] established a precedent for combining IS and UCD approaches and offered a new glossary of UCD strategies IS experts could use. In this commentary, we build upon this work by combining IS and HCD approaches and offering a how-to guide for IS experts to operationalize implementation strategies using
HCD methods. Combining IS and HCD approaches is novel to health care research and practice, and we
believe that these complementary approaches can be applied together to optimize the integration of
evidence-based practices within clinical and public health settings.